Treatment of Bovine Staphylococcal Mastitis with Staphylococcal Toxoid

The Treatment of Furunculosis and Other Staphylococcal Lesions by Staphylococcal Toxoid

THE discovery that many strainis of staphylococci produce a toxini (Neisser and XVNlechsberg, 19011; Kraus anid Pibream, 19062; Parker, 19243; and Burnet, 19294) has thrown fresh light on the problem of the treatment of staphylococcal lesions. From staphylococcal toxin, Panton, Valentine, and Dix (1931)5 successfully prepared staphylococcal toxoid. In 1933 Parish6 found that staphylococcal toxo...

Staphylococcal Mastitis in Bovines and Some Properties of Staphylococcal Isolates

Milk samples of 100 clinically mastitic bovines (50 each from buffaloes and cows) were processed for bacterial isolation. A total of 90 bacterial isolates, including 33 of staphylococci and 57 of other bacterial species were recovered. Of the 33 staphylococcal isolates, 23 were identified as Staphylococcus aureus and 10 as Staphylococcus epidermidis. All Staphylococcus aureus isolates were posi...

Evaluation of a Combined Vaccine against Staphylococcal Mastitis in Ewes

The effectiveness of combined staphylococcal vaccine (CSV), prepared from Staphylococcus aureus and coagulase negative staphylococci (CNS: Staphylococcus epidermidis, S. simulans, S. saprophyticus), on staphylococcal mastitis in sheep was determined. The group of pregnant sheep was vaccinated subcutaneously into supramammary lymph node twice at 3 week interval. Similarly, sterile saline was adm...

Treatment of Generalized Staphylococcal Infections.

Lysis of staphylococcal mastitis pathogens by bacteriophage phi11 endolysin.

The Staphylococcus aureus bacteriophage phi11 endolysin has two peptidoglycan hydrolase domains (endopeptidase and amidase) and an SH3b cell wall-binding domain. In turbidity reduction assays, the purified protein can lyse untreated staphylococcal mastitis pathogens, Staphylococcus aureus and coagulase-negative staphylococci (Staphylococcus chronogenes, Staphylococcus epidermidis, Staphylococcu...